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Daniel D Bikle Selected Research

IGF Type 1 Receptor (IGF 1 Receptor)

6/2012Insulin like growth factor-I: a critical mediator of the skeletal response to parathyroid hormone.
7/2011IGF-1R signaling in chondrocytes modulates growth plate development by interacting with the PTHrP/Ihh pathway.
9/2007IGF-I receptor is required for the anabolic actions of parathyroid hormone on bone.

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Daniel D Bikle Research Topics

Disease

29Neoplasms (Cancer)
12/2021 - 12/2004
13Skin Neoplasms (Skin Cancer)
01/2016 - 12/2004
6Vitamin D Deficiency
01/2022 - 01/2011
6Rickets (Rachitis)
01/2019 - 01/2002
5Infections
01/2022 - 03/2007
5Wounds and Injuries (Trauma)
07/2020 - 03/2007
5Osteomalacia
01/2019 - 12/2007
4Hypercalcemia (Milk Alkali Syndrome)
06/2018 - 06/2009
4Carcinogenesis
06/2017 - 11/2012
3Alopecia (Baldness)
01/2016 - 01/2002
2COVID-19
01/2022 - 01/2022
2Bacterial Infections (Bacterial Infection)
01/2022 - 07/2008
2Squamous Cell Carcinoma of Head and Neck
12/2020 - 06/2017
2Colonic Neoplasms (Colon Cancer)
02/2016 - 05/2013
2Breast Neoplasms (Breast Cancer)
05/2014 - 03/2003
2Autoimmune Diseases (Autoimmune Disease)
05/2013 - 07/2009
2Bone Resorption
06/2012 - 09/2006
2Skin Diseases (Skin Disease)
04/2012 - 10/2003
2Osteoporosis
12/2007 - 06/2003
2Body Weight (Weight, Body)
09/2007 - 05/2006
2Squamous Cell Carcinoma (Epidermoid Carcinoma)
05/2003 - 01/2003
1Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
01/2022
1Respiratory Tract Infections (Respiratory Tract Infection)
01/2022
1Sarcoidosis (Schaumann Disease)
06/2018
1Sunburn
10/2017
1Mouth Neoplasms (Oral Cancer)
06/2017
1Hypoxia (Hypoxemia)
01/2017
1Hyperoxia
01/2017
1Avian Sarcoma
04/2016
1Basal Cell Carcinoma (Rodent Ulcer)
01/2016
1Ovarian Neoplasms (Ovarian Cancer)
11/2015
1Leukemia
11/2015
1Atrophy
06/2014
1Colorectal Neoplasms (Colorectal Cancer)
05/2014
1Melanoma (Melanoma, Malignant)
11/2013
1Obesity
05/2013
1Metabolic Bone Diseases (Osteopenia)
06/2012
1Darier Disease (Darier's Disease)
04/2012
1Ankylosis
12/2011

Drug/Important Bio-Agent (IBA)

28Vitamin DFDA LinkGeneric
01/2022 - 01/2002
16Calcitriol Receptors (Calcitriol Receptor)IBA
01/2020 - 10/2005
11CalciumIBA
12/2020 - 05/2003
10hydroxide ionIBA
01/2022 - 01/2003
8CateninsIBA
12/2020 - 07/2013
81,25-dihydroxyvitamin DIBA
12/2012 - 12/2004
5CarcinogensIBA
12/2021 - 07/2013
525-Hydroxyvitamin D3 1-alpha-Hydroxylase (25 Hydroxyvitamin D3 1 alpha Hydroxylase)IBA
12/2021 - 03/2007
4Long Noncoding RNAIBA
01/2021 - 03/2014
4Calcium-Sensing ReceptorsIBA
07/2020 - 04/2015
4Insulin-Like Growth Factor I (IGF-1)IBA
06/2012 - 03/2004
3Cadherins (E-Cadherin)IBA
12/2020 - 01/2017
3Proteins (Proteins, Gene)FDA Link
06/2017 - 10/2003
3LigandsIBA
02/2016 - 11/2011
3Cholecalciferol (Vitamin D3)FDA Link
03/2014 - 03/2007
3MineralsIBA
05/2013 - 06/2003
3IGF Type 1 Receptor (IGF 1 Receptor)IBA
06/2012 - 09/2007
2Delta CateninIBA
12/2020 - 06/2017
2Dietary CalciumIBA
07/2020 - 06/2017
2Phosphates (Orthophosphate)IBA
01/2019 - 06/2012
2IntegrinsIBA
01/2018 - 04/2016
2Calcitriol (Calcijex)FDA LinkGeneric
02/2016 - 07/2013
2Vitamin D3 24-HydroxylaseIBA
02/2016 - 08/2015
2involucrinIBA
01/2016 - 05/2003
2PS121912IBA
11/2015 - 10/2014
2DNA (Deoxyribonucleic Acid)IBA
07/2013 - 10/2008
29,10-Dimethyl-1,2-benzanthraceneIBA
07/2013 - 11/2011
2Cyclin D1IBA
07/2013 - 10/2010
1EnzymesIBA
12/2021
1Phospholipases (Phospholipase)IBA
12/2020
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
12/2020
1Epidermal Growth Factor (EGF)IBA
12/2020
1Hyaluronic Acid (Hyaluronan)IBA
01/2020
1Estrogen ReceptorsIBA
01/2018
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2017
1Desmoglein 1IBA
01/2017
1CytokinesIBA
11/2016
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
11/2016
1Phosphotransferases (Kinase)IBA
04/2016
1Focal Adhesion Protein-Tyrosine KinasesIBA
04/2016
1calcitroic acidIBA
02/2016
1Cathepsin LIBA
01/2016
1Desmoglein 3IBA
01/2016
1LactoseFDA LinkGeneric
01/2016
1loricrinIBA
01/2016
1S100 Calcium Binding Protein GIBA
01/2016
1JNK Mitogen-Activated Protein KinasesIBA
11/2015
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
11/2015
1Protein Kinases (Protein Kinase)IBA
11/2015
1Mitogen-Activated Protein KinasesIBA
11/2015
1Caspase 3 (Caspase-3)IBA
11/2015
1Ion Channels (Ion Channel)IBA
06/2014
1Biomarkers (Surrogate Marker)IBA
03/2014
1TamoxifenFDA LinkGeneric
07/2013
1Cre recombinaseIBA
07/2013
1Parathyroid Hormone-Related ProteinIBA
05/2012
1Antimicrobial PeptidesIBA
05/2012
1SphingolipidsIBA
04/2012
1Adenosine Triphosphatases (ATPase)IBA
04/2012
1ectonucleotide pyrophosphatase phosphodiesterase 1IBA
12/2011

Therapy/Procedure

1Transjugular Intrahepatic Portasystemic Shunt
10/2017